Interferon-gamma is not a universal requirement for islet allograft survival
Nicolls, M. R., Coulombe, M., Diamond, A. S., Beilke, J., & Gill, R. G. (2002). Interferon-gamma is not a universal requirement for islet allograft survival. TRANSPLANTATION, 74(4), 472–477.

CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways
Nicolls, M. R., Coulombe, M., Beilke, J., Gelhuas, H. C., & Gill, R. G. (2002). CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways. JOURNAL OF IMMUNOLOGY, 169(9), 4831–39.

Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets
Nicolls, M. R., D'Antonio, J. M., Hutton, J. C., Gill, R. G., Czwornog, J. L., & Duncan, M. W. (2003). Proteomics as a tool for discovery: Proteins implicated in Alzheimer's disease are highly expressed in normal pancreatic islets. JOURNAL OF PROTEOME RESEARCH, 2(2), 199–205.

Gene microarray study corroborates proteomic findings in rodent islet cells
Cardozo, A. K., Berthou, L., Kruhoffer, M., Orntoft, T., Nicolls, M. R., & Eizirik, D. L. (2003). Gene microarray study corroborates proteomic findings in rodent islet cells. JOURNAL OF PROTEOME RESEARCH, 2(5), 553–555.

Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation
Zamora, M. R., Nicolls, M. R., Hodges, T. N., Marquesen, J., Astor, T., Grazia, T., & Weill, D. (2004). Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation. AMERICAN JOURNAL OF TRANSPLANTATION, 4(10), 1635–1642.

An animal model of autoimmune emphysema
Taraseviciene-Stewart, L., Scerbavicius, R., Chloe, K. H., Moore, M., Sullivan, A., Nicolls, M. R., … Voelkel, N. F. (2005). An animal model of autoimmune emphysema. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 171(7), 734–742.

Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis
Murakawa, T., Kerklo, M. M., Zamora, M. R., Wei, Y., Gill, R. G., Henson, P. M., … Nicolls, M. R. (2005). Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: Implications for the role of respiratory epithelium as a modulator of fibrosis. JOURNAL OF IMMUNOLOGY, 174(7), 3869–79.

Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses?
Douglas, I. S., & Nicolls, T. R. (2005). Chemokine-mediated angiogenesis: an essential link in the evolution of airway fibroses? JOURNAL OF CLINICAL INVESTIGATION, 115(5), 1133–36.

The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease
Nicolls, M. R. (2004). The Clinical and Biological Relationship between Type II Diabetes Mellitus and Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH, 1(1), 47–54.

Type 2 diabetes mellitus as a conformational disease.
Hayden, M. R., Tyagi, S. C., Kerklo, M. M., & Nicolls, M. R. (2005). Type 2 diabetes mellitus as a conformational disease. JOP : Journal of the Pancreas, 6(4), 287–302.

Autoimmunity and pulmonary hypertension: a perspective
Nicolls, M. R., Taraseviciene-Stewart, L., Rai, P. R., Badesch, D. B., & Voelkel, N. F. (2005). Autoimmunity and pulmonary hypertension: a perspective. EUROPEAN RESPIRATORY JOURNAL, 26(6), 1110–18.

The protective role of T-lymphocytes in pulmonary vascular remodeling
Taraseviciene-Stewart, L., Kraskauskas, D., Scerbavicins, R., Burns, N., Cool, C. D., Nicolls, M. R., & Voelkel, N. F. (2005). The protective role of T-lymphocytes in pulmonary vascular remodeling. CHEST, 128(6), 571S–572S.

LFA-1 (CD11a) as a therapeutic target
Nicolls, M. R., & Gill, R. G. (2006). LFA-1 (CD11a) as a therapeutic target. AMERICAN JOURNAL OF TRANSPLANTATION, 6(1), 27–36.

Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma
El Gazzar, M., El Mezayen, R., Nicolls, M. R., Marecki, J. C., & Dreskin, S. C. (2006). Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760(7), 1088–1095.

Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation
El Gazzar, M., El Mezayen, R., Marecki, J. C., Nicolls, M. R., Canastar, A., & Dreskin, S. C. (2006). Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation. INTERNATIONAL IMMUNOPHARMACOLOGY, 6(7), 1135–1142.

Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation
El Mezayen, R., El Gazzar, M., Nicolls, M. R., Marecki, J. C., Dreskin, S. C., & Nomiyama, H. (2006). Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. IMMUNOLOGY LETTERS, 106(1), 72–81.

Mechanisms of autoimmune emphysema.
Taraseviciene-Stewart, L., Burns, N., Kraskauskas, D., Nicolls, M. R., Tuder, R. M., & Voelkel, N. F. (2006). Mechanisms of autoimmune emphysema. Proceedings of the American Thoracic Society, 3(6), 486–487.

Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?
Taraseviciene-Stewart, L., Douglas, I. S., Nana-Sinkam, P. S., Lee, J. D., Tuder, R. M., Nicolls, M. R., & Voelkel, N. F. (2006). Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease? Proceedings of the American Thoracic Society, 3(8), 687–690.

Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation
El Gazzar, M. A., El Mezayen, R., Nicolls, M. R., & Dreskin, S. C. (2007). Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(4), 556–564.

Angiogenesis in chronic lung disease
Voelkel, N. F., Douglas, I. S., & Nicolls, M. (2007). Angiogenesis in chronic lung disease. CHEST, 131(3), 874–879.

The matrix comes to lung transplantation
Babu, A. N., & Nicolls, M. R. (2007). The matrix comes to lung transplantation. TRANSPLANTATION, 83(6), 683–684.

Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens
Hall, B. M., Plain, K. M., Verma, N. D., Tran, G. T., Boyd, R., Robinson, C. M., … Hodgkinson, S. J. (2007). Transfer of allograft specific tolerance requires CD4(+)CD25(+)T cells but not interleukin-4 or transforming growth factor-beta and cannot induce tolerance to linked antigens. TRANSPLANTATION, 83(8), 1075–1084.

Oxidant stress, immune dysregulation, and vascular function in type I diabetes
Nicolls, M. R., Haskins, K., & Flores, S. C. (2007). Oxidant stress, immune dysregulation, and vascular function in type I diabetes. ANTIOXIDANTS & REDOX SIGNALING, 9(7), 879–889.

Hypoxia and the lung: Beyond hypoxic vasoconstriction
Nicolls, M. R., & Voelkel, N. F. (2007). Hypoxia and the lung: Beyond hypoxic vasoconstriction. ANTIOXIDANTS & REDOX SIGNALING, 9(6), 741–743.

Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin
El Mezayen, R., El Gazzar, M., Seeds, M. C., McCall, C. E., Dreskin, S. C., & Nicolls, M. R. (2007). Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. IMMUNOLOGY LETTERS, 111(1), 36–44.

Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension
Ulrich, S., Nicolls, M. R., Taraseviciene, L., Speich, R., & Voelkel, N. (2008). Increased regulatory and decreased CD8+ cytotoxic T cells in the blood of patients with idiopathic pulmonary arterial hypertension. RESPIRATION, 75(3), 272–280.

Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis
Babu, A. N., Murakawa, T., Thurman, J. M., Miller, E. J., Henson, P. M., Zamora, M. R., … Nicolls, M. R. (2007). Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. JOURNAL OF CLINICAL INVESTIGATION, 117(12), 3774–3785.

Lung Transplant Airway Hypoxia A Diathesis to Fibrosis?
Dhillon, G. S., Zamora, M. R., Roos, J. E., Sheahan, D., Sista, R. R., van der Starre, P., … Nicolls, M. R. (2010). Lung Transplant Airway Hypoxia A Diathesis to Fibrosis? AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(2), 230–36.

Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype
Chung, L., Liu, J., Parsons, L., Hassoun, P. M., McGoon, M., Badesch, D. B., … Zamanian, R. T. (2010). Characterization of Connective Tissue Disease-Associated Pulmonary Arterial Hypertension From REVEAL Identifying Systemic Sclerosis as a Unique Phenotype. CHEST, 138(6), 1383–94.

Bronchial blood supply after lung transplantation without bronchial artery revascularization
Nicolls, M. R., & Zamora, M. R. (2010). Bronchial blood supply after lung transplantation without bronchial artery revascularization. CURRENT OPINION IN ORGAN TRANSPLANTATION, 15(5), 563–67.

Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report
Erzurum, S., Rounds, S. I., Stevens, T., Aldred, M., Aliotta, J., Archer, S. L., … Moore, T. M. (2010). Strategic Plan for Lung Vascular Research An NHLBI-ORDR Workshop Report. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(12), 1554–62.

Immunomodulatory strategies prevent the development of autoimmune emphysema
Hanaoka, M., Nicolls, M. R., Fontenot, A. P., Kraskauskas, D., Mack, D. G., Kratzer, A., … Taraseviciene-Stewart, L. (2010). Immunomodulatory strategies prevent the development of autoimmune emphysema. RESPIRATORY RESEARCH, 11.

Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice
Hilgendorff, A., Parai, K., Ertsey, R., Jain, N., Navarro, E. F., Peterson, J. L., … Bland, R. D. (2011). Inhibiting Lung Elastase Activity Enables Lung Growth in Mechanically Ventilated Newborn Mice. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 184(5), 537–46.

Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
Jiang, X., Khan, M. A., Tian, W., Beilke, J., Natarajan, R., Kosek, J., … Nicolls, M. R. (2011). Adenovirus-mediated HIF-1 alpha gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection. JOURNAL OF CLINICAL INVESTIGATION, 121(6), 2336–49.

Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension
Tamosiuniene, R., Tian, W., Dhillon, G., Wang, L., Sung, Y. K., Gera, L., … Nicolls, M. R. (2011). Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension. CIRCULATION RESEARCH, 109(8), 867–U120.

CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants
Khan, M. A., Jiang, X., Dhillon, G., Beilke, J., Holers, V. M., Atkinson, C., … Nicolls, M. R. (2011). CD4(+) T Cells and Complement Independently Mediate Graft Ischemia in the Rejection of Mouse Orthotopic Tracheal Transplants. CIRCULATION RESEARCH, 109(11), 1290–U256.

A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects
Gomez-Arroyo, J., Saleem, S. J., Mizuno, S., Syed, A. A., Bogaard, H. J., Abbate, A., … Voelkel, N. F. (2012). A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 302(10), L977–L991.

Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth.
Hilgendorff, A., Parai, K., Ertsey, R., Juliana Rey-Parra, G., Thébaud, B., Tamosiuniene, R., … Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. American Journal of Physiology. Lung Cellular and Molecular Physiology, 303(3), L215–27.

Pathobiology of pulmonary arterial hypertension and right ventricular failure
Voelkel, N. F., Gomez-Arroyo, J., Abbate, A., Bogaard, H. J., & Nicolls, M. R. (2012). Pathobiology of pulmonary arterial hypertension and right ventricular failure. EUROPEAN RESPIRATORY JOURNAL, 40(6), 1555–1565.

Regulatory T Cells and Pulmonary Hypertension
Tamosiuniene, R., & Nicolls, M. R. (2011). Regulatory T Cells and Pulmonary Hypertension. TRENDS IN CARDIOVASCULAR MEDICINE, 21(6), 166–71.

Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization
Mizuno, S., Farkas, L., Al Husseini, A., Farkas, D., Gomez-Arroyo, J., Kraskauskas, D., … Voelkel, N. F. (2012). Severe Pulmonary Arterial Hypertension Induced by SU5416 and Ovalbumin Immunization. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 47(5), 679–687.

New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation
Khan, M. A., Dhillon, G., Jiang, X., Lin, Y.-C., & Nicolls, M. R. (2012). New methods for monitoring dynamic airway tissue oxygenation and perfusion in experimental and clinical transplantation. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(10), L861–L869.

Potential for overuse of corticosteroids and vasopressin in septic shock.
Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. Critical Care (London, England), 16(5), 447.

New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis.
Nicolls, M. R., Mizuno, S., Taraseviciene-Stewart, L., Farkas, L., Drake, J. I., Al Husseini, A., … Bogaard, H. J. (2012). New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulmonary Circulation, 2(4), 434–42.

Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis
Deane, K. D., & Nicolls, M. R. (2013). Editorial: Developing Better Biomarkers for Connective Tissue DiseaseAssociated Interstitial Lung Disease: Citrullinated Hsp90 Autoantibodies in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65(4), 864–868.

Complement-mediated microvascular injury leads to chronic rejection.
Khan, M. A., & Nicolls, M. R. (2013). Complement-mediated microvascular injury leads to chronic rejection. Advances in Experimental Medicine and Biology, 735, 233–46.

Targeting complement component 5a promotes vascular integrity and limits airway remodeling.
Khan, M. A., Maasch, C., Vater, A., Klussmann, S., Morser, J., Leung, L. L., … Nicolls, M. R. (2013). Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proceedings of the National Academy of Sciences of the United States of America, 110(15), 6061–6066.

INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES
WOODLEY, S. L., Gurley, K. E., HOFFMANN, S. L., Nicolls, M. R., Hagberg, R., CLAYBERGER, C., … Strober, S. (1993). INDUCTION OF TOLERANCE TO HEART ALLOGRAFTS IN RATS USING POSTTRANSPLANT TOTAL LYMPHOID IRRADIATION AND ANTI-T CELL ANTIBODIES. TRANSPLANTATION, 56(6), 1443–47.

INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY
Nicolls, M. R., AVERSA, G. G., Pearce, N. W., Spinelli, A., Berger, M. F., Gurley, K. E., & Hall, B. M. (1993). INDUCTION OF LONG-TERM SPECIFIC TOLERANCE TO ALLOGRAFTS IN RATS BY THERAPY WITH AN ANTI-CD3-LIKE MONOCLONAL-ANTIBODY. TRANSPLANTATION, 55(3), 459–68.

Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome
Nicolls, M. R., Terada, L. S., Tuder, R. M., Prindiville, S. A., & Schwarz, M. I. (1998). Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 158(4), 1302–5.

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling.
Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling. (2007). Am J Respir Crit Care Med, 175(12).

Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth
Hilgendorff, A., Parai, K., Ertsey, R., Rey-Parra, G. J., Thebaud, B., Tamosiuniene, R., … Bland, R. D. (2012). Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 303(3), L215–L227.

Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response
Chung, L., Liu, J., Parsons, L. S., Hassoun, P. M., McGoon, M. D., Badesch, D. B., … Zamanian, R. T. (2011). Survival in Pulmonary Hypertension Registries The Importance of Incident Cases Response. CHEST, 139(6), 1548–49.

Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension
Tamosiuniene, R., Long, C., Ambler, K., Sung, Y., Gera, L., Wang, L., & Nicolls, M. (2009). Immune Reconstitution Prevents Autoimmune Inflammation and Right Ventricular Remodeling in Immunodeficiency-Associated Pulmonary Hypertension. CIRCULATION, 120(18), S1135–S1135.

Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells
Tamosiuniene, R., Long, C., Ambler, K., Wang, L., Gera, L., Sung, Y., & Nicolls, M. (2009). Prevention of Adverse Right Ventricular Remodeling and Autoimmune Inflammation after Splenocyte Therapy in Pulmonary Hypertension: Contribution of HOX11+, C-kit+, FOXP3+Cells. Presented at the 9th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, SAN FRANCISCO,CA: ACADEMIC PRESS INC ELSEVIER SCIENCE.

The Role of C3 Activation in Airway Hypoxia and Ischemia in Murine Model of Orthotopic Tracheal Transplantation
Khan, M. A., Jiang, X., Atkinson, C., Tomlinson, S., & Nicolls, M. R. (2011). The Role of C3 Activation in Airway Hypoxia and Ischemia in Murine Model of Orthotopic Tracheal Transplantation. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 30(4), S130–S131.

Potential for overuse of corticosteroids and vasopressin in septic shock
Hsu, J. L., Liu, V., Patterson, A. J., Martin, G. S., Nicolls, M. R., & Russell, J. A. (2012). Potential for overuse of corticosteroids and vasopressin in septic shock. CRITICAL CARE, 16(5).

Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation.
Konoeda, C., Koinuma, D., Morishita, Y., Sano, A., Nagayama, K., Motomura, N., … Murakawa, T. (2013). Epithelial to mesenchymal transition in murine tracheal allotransplantation: an immunohistochemical observation. Transplantation Proceedings, 45(5), 1797–1801.

Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus.
Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., de Jesus Perez, V., … Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. Journal of Molecular Medicine (Berlin, Germany).

Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension
Tian, W., Jiang, X., Tamosiuniene, R., Sung, Y. K., Qian, J., Dhillon, G., … Nicolls, M. R. (2013). Blocking Macrophage Leukotriene B-4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension. SCIENCE TRANSLATIONAL MEDICINE, 5(200).

Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus
Jiang, X., Hsu, J. L., Tian, W., Yuan, K., Olcholski, M., Perez, V. D. J., … Nicolls, M. R. (2013). Tie2-dependent VHL knockdown promotes airway microvascular regeneration and attenuates invasive growth of Aspergillus fumigatus. JOURNAL OF MOLECULAR MEDICINE-JMM, 91(9), 1081–93.

Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia
Hsu, J. L., Khan, M. A., Sobel, R. A., Jiang, X., Clemons, K. V., Nguyen, T. T., … Nicolls, M. R. (2013). Aspergillus fumigatus Invasion Increases with Progressive Airway Ischemia. PLOS ONE, 8(10).

Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles.
Jiang, X., Malkovskiy, A. V., Tian, W., Sung, Y. K., Sun, W., Hsu, J. L., … Nicolls, M. R. (2014). Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. Biomaterials, 35(2), 803–13.

The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3 ' Untranslated Region-Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue
Singh, A. B., Li, H., Kan, C. F. K., Dong, B., Nicolls, M. R., & Liu, J. (2014). The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3 ' Untranslated Region-Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 34(1), 8-?

Application of a non-amplification-based technology to detect invasive fungal pathogens
Hsu, J. L., Binkley, J., Clemons, K. V., Stevens, D. A., Nicolls, M. R., & Holodniy, M. (2014). Application of a non-amplification-based technology to detect invasive fungal pathogens. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 78(2), 137–40.

Temporal response of the human virome to immunosuppression and antiviral therapy.
De Vlaminck, I., Khush, K. K., Strehl, C., Kohli, B., Luikart, H., Neff, N. F., … Quake, S. R. (2013). Temporal response of the human virome to immunosuppression and antiviral therapy. Cell, 155(5), 1178–87.

Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock
Beraud, A.-S., Guillamet, C. V., Hammes, J. L., Meng, L., Nicolls, M. R., & Hsu, J. L. (2014). Efficacy of Transthoracic Echocardiography for Diagnosing Heart Failure in Septic Shock. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 347(4), 295–98.

Working toward immune tolerance in lung transplantation.
Jiang, X., & Nicolls, M. R. (2014). Working toward immune tolerance in lung transplantation. The Journal of Clinical Investigation, 1–4.

Complement components as potential therapeutic targets for asthma treatment
Khan, M. A., Nicolls, M. R., Surguladze, B., & Saadoun, I. (2014). Complement components as potential therapeutic targets for asthma treatment. RESPIRATORY MEDICINE, 108(4), 543–49.

Leukotrienes in pulmonary arterial hypertension.
Tian, W., Jiang, X., Sung, Y. K., Qian, J., Yuan, K., & Nicolls, M. R. (2014). Leukotrienes in pulmonary arterial hypertension. Immunologic Research, 58(2-3), 387–93.

Macrophages in solid organ transplantation.
Jiang, X., Tian, W., Sung, Y. K., Qian, J., & Nicolls, M. R. (2014). Macrophages in solid organ transplantation. Vascular Cell, 6(1), 5-?

Nuclear Factor ?B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats.
Farkas, D., Alhussaini, A. A., Kraskauskas, D., Kraskauskiene, V., Cool, C. D., Nicolls, M. R., … Farkas, L. (2014). Nuclear Factor ?B Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats. American Journal of Respiratory Cell and Molecular Biology, 51(3), 413–425.

Graft microvascular disease in solid organ transplantation.
Jiang, X., Sung, Y. K., Tian, W., Qian, J., Semenza, G. L., & Nicolls, M. R. (2014). Graft microvascular disease in solid organ transplantation. Journal of Molecular Medicine (Berlin, Germany), 92(8), 797–810.

Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
Rabinovitch, M., Guignabert, C., Humbert, M., & Nicolls, M. R. (2014). Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension. CIRCULATION RESEARCH, 115(1), 165–75.

Traumatic Brain Injury: Lungs in a RAGE.
Nicolls, M. R., & Laubach, V. E. (2014). Traumatic Brain Injury: Lungs in a RAGE. Science Translational Medicine, 6(252), 252fs34.

Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry.
Chung, L., Farber, H. W., Benza, R., Miller, D. P., Parsons, L., Hassoun, P. M., … Zamanian, R. T. (2014). Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry. Chest, 146(6), 1494–1504.

Impact of the lung allocation score on survival beyond 1 year.
Maxwell, B. G., Levitt, J. E., Goldstein, B. A., Mooney, J. J., Nicolls, M. R., Zamora, M., … Dhillon, G. S. (2014). Impact of the lung allocation score on survival beyond 1 year. American Journal of Transplantation , 14(10), 2288–94.

Impact of the Lung Allocation Score on Survival Beyond 1 Year
Maxwell, B. G., Levitt, J. E., Goldstein, B. A., Mooney, J. J., Nicolls, M. R., Zamora, M., … Dhillon, G. S. (2014). Impact of the Lung Allocation Score on Survival Beyond 1 Year. AMERICAN JOURNAL OF TRANSPLANTATION, 14(10), 2288–94.

Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis.
Yuan, K., Orcholski, M. E., Panaroni, C., Shuffle, E. M., Huang, N. F., Jiang, X., … de Jesus Perez, V. A. (2015). Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis. American Journal of Pathology, 185(1), 69–84.

Increased Resource Use in Lung Transplant Admissions in the Lung Allocation Score Era
Maxwelll, B. G., Mooney, J. J., Lee, P. H. U., Levitt, J. E., Chhatwani, L., Nicolls, M. R., … Dhillon, G. S. (2015). Increased Resource Use in Lung Transplant Admissions in the Lung Allocation Score Era. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(3), 302–8.

Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection
Jiang, X., Nguyen, T. T., Tian, W., Sung, Y. K., Yuan, K., Qian, J., … Nicolls, M. R. (2015). Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection. AMERICAN JOURNAL OF TRANSPLANTATION, 15(7), 1768–81.

Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling
Nickel, N. P., Spiekerkoetter, E., Gu, M., Li, C. G., Li, H., Kaschwich, M., … Rabinovitch, M. (2015). Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(11), 1273–86.

Critical pathways leading to obliterative bronchiolitis in lung allografts
Babu, A. N., & Nicolls, M. R. (2006). Critical pathways leading to obliterative bronchiolitis in lung allografts. CURRENT OPINION IN ORGAN TRANSPLANTATION, 11(5), 483–489.

Recognition and treatment of diffuse panbronchiolitis
Nicolls, M. R., Weiss, S. M., & Schwarz, M. I. (1998). Recognition and treatment of diffuse panbronchiolitis. INFECTIONS IN MEDICINE, 15(9), 657–662.

Noninvasive monitoring of infection and rejection after lung transplantation.
De Vlaminck, I., Martin, L., Kertesz, M., Patel, K., Kowarsky, M., Strehl, C., … Quake, S. R. (2015). Noninvasive monitoring of infection and rejection after lung transplantation. Proceedings of the National Academy of Sciences of the United States of America, 112(43), 13336–41.

Leukotriene B-4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension
Qian, J., Tian, W., Jiang, X., Tamosiuniene, R., Sung, Y. K., Shuffle, E. M., … Nicolls, M. R. (2015). Leukotriene B-4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension. HYPERTENSION, 66(6), 1227–39.

Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States
Mooney, J. J., Hedlin, H., Mohabir, P. K., Vazquez, R., Nguyen, J., Ha, R., … Dhillon, G. S. (2016). Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States. AMERICAN JOURNAL OF TRANSPLANTATION, 16(4), 1207–15.

A Critical Role for Airway Microvessels in Lung Transplantation.
Nicolls, M. R., Dhillon, G. S., & Daddi, N. (2016). A Critical Role for Airway Microvessels in Lung Transplantation. American Journal of Respiratory and Critical Care Medicine, 193(5), 479–81.

Microvascular injury after lung transplantation
Nicolls, M. R., Hsu, J. L., & Jiang, X. (2016). Microvascular injury after lung transplantation. CURRENT OPINION IN ORGAN TRANSPLANTATION, 21(3), 279–84.

Effect of Transplant Center Volume on Cost and Readmissions in Medicare Lung Transplant Recipients.
Mooney, J. J., Weill, D., Boyd, J. H., Nicolls, M. R., Bhattacharya, J., & Dhillon, G. S. (2016). Effect of Transplant Center Volume on Cost and Readmissions in Medicare Lung Transplant Recipients. Annals of the American Thoracic Society, 13(7), 1034–41.

Challenges and opportunities in treating inflammation associated with pulmonary hypertension.
Voelkel, N. F., Tamosiuniene, R., & Nicolls, M. R. (2016). Challenges and opportunities in treating inflammation associated with pulmonary hypertension. Expert Review of Cardiovascular Therapy, 14(8), 939–51.

Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis.
Lin, Y.-C., Sung, Y. K., Jiang, X., Peters-Golden, M., & Nicolls, M. R. (2016). Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis. American Journal of Transplantation .

Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip.
Jothimuthu, P., Hsu, J. L., Chen, R., Inayathullah, M., Pothineni, V. R., Jan, A., … Nicolls, M. R. (2016). Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip. ChemNanoMat : Chemistry of Nanomaterials for Energy, Biology and More, 2(9), 904–910.

Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis
Yuan, K., Orcholski, M. E., Panaroni, C., Shuffle, E. M., Huang, N. F., Jiang, X., … Perez, V. A. J. (2015). Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis. AMERICAN JOURNAL OF PATHOLOGY, 185(1), 69–84.

Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip
Jothimuthu, P., Hsu, J. L., Chen, R., Inayathullah, M., Pothineni, V. R., Jan, A., … Nicolls, M. R. (2016). Enhanced Electrochemical Sensing with Carbon Nanotubes Modified with Bismuth and Magnetic Nanoparticles in a Lab-on-a-Chip. CHEMNANOMAT, 2(9), 904–10.

Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.
Lama, V. N., Belperio, J. A., Christie, J. D., El-Chemaly, S., Fishbein, M. C., Gelman, A. E., … Nicolls, M. R. (2017). Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop. JCI Insight, 2(9).

Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension
Bonnet, S., Provencher, S., Guignabert, C., Perros, F., Boucherat, O., Schermuly, R. T., … Humbert, M. (2017). Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195(5), 583–95.

Leukotriene B-4 antagonism ameliorates experimental lymphedema
Tian, W., Rockson, S. G., Jiang, X., Kim, J., Begaye, A., Shuffle, E. M., … Nicolls, M. R. (2017). Leukotriene B-4 antagonism ameliorates experimental lymphedema. SCIENCE TRANSLATIONAL MEDICINE, 9(389).

Aspergillus-related pulmonary diseases in lung transplantation
Pasupneti, S., Manouvakhova, O., Nicolls, M. R., & Hsu, J. L. (2017). Aspergillus-related pulmonary diseases in lung transplantation. MEDICAL MYCOLOGY, 55(1), 96–102.

Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis
Lin, Y.-C., Sung, Y. K., Jiang, X., Peters-Golden, M., & Nicolls, M. R. (2017). Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis. AMERICAN JOURNAL OF TRANSPLANTATION, 17(5), 1229–41.

The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension
Nicolls, M. R., & Voelkel, N. F. (2017). The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195(10), 1292–99.

Upregulation of HERV-K is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.
Saito, T., Miyagawa, K., Chen, S.-Y. Y., Tamosiuniene, R., Wang, L., Sharp, O., … Rabinovitch, M. (2017). Upregulation of HERV-K is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension. Circulation.

Introduction to the 59th Annual Thomas L. Petty Aspen Lung Conference. Lung Transplantation: Opportunities for Repair and Regeneration.
Zamora, M. R., Martinu, T., & Nicolls, M. R. (2017). Introduction to the 59th Annual Thomas L. Petty Aspen Lung Conference. Lung Transplantation: Opportunities for Repair and Regeneration. Annals of the American Thoracic Society, 14(Supplement_3), S209.

Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis
de Bourcy, C. F. A., Dekker, C. L., Davis, M. M., Nicolls, M. R., & Quake, S. R. (2017). Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis. Dynamics of the Human Antibody Repertoire after B Cell Depletion in Systemic Sclerosis, 2(15).

Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis.
de Bourcy, C. F., Dekker, C. L., Davis, M. M., Nicolls, M. R., & Quake, S. R. (2017). Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis. Science Immunology, 2(15).

Lymphatic Dysfunction, Leukotrienes, and Lymphedema.
Jiang, X., Nicolls, M. R., Tian, W., & Rockson, S. G. (2017). Lymphatic Dysfunction, Leukotrienes, and Lymphedema. Annual Review of Physiology.

Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.
Blum, L. K., Cao, R. R., Sweatt, A. J., Bill, M., Lahey, L. J., Hsi, A. C., … Robinson, W. H. (2018). Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. European Journal of Immunology.

Microhemorrhage-associated tissue iron enhances the risk forAspergillus fumigatusinvasion in a mouse model of airway transplantation.
Hsu, J. L., Manouvakhova, O. V., Clemons, K. V., Inayathullah, M., Tu, A. B., Sobel, R. A., … Nicolls, M. R. (2018). Microhemorrhage-associated tissue iron enhances the risk forAspergillus fumigatusinvasion in a mouse model of airway transplantation. Science Translational Medicine, 10(429).

Nordihydroguaiaretic acid, a lignan from Larrea tridentata (Creosote bush) protects against ALIOS diet-induced metabolic dysfunction in mice.
Chan, J. K., Bittner, S., Bittner, A., Atwal, S., Shen, W.-J. J., Inayathullah, M., … Azhar, S. (2018). Nordihydroguaiaretic acid, a lignan from Larrea tridentata (Creosote bush) protects against ALIOS diet-induced metabolic dysfunction in mice. The Journal of Pharmacology and Experimental Therapeutics.

A Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.
Tamosiuniene, R., Manouvakhova, O., Mesange, P., Saito, T., Qian, J., Sanyal, M., … Nicolls, M. R. (2018). A Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. Circulation Research.

Circulating Elastase Confers A High Risk For The Development Of Bronchiolitis Obliterans Syndrome
Milla, C. E., Zirbes, J. M., Yacob, A., Tian, L., Zamanian, R. T., Bental-Roof, M., … Nicolls, M. (2016). Circulating Elastase Confers A High Risk For The Development Of Bronchiolitis Obliterans Syndrome. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Impact Of Non Invasive Open Ventilation (niov) On Dyspnea And Quality Of Life In Patients With Chronic Obstructive Pulmonary Disease (COPD) And Idiopathic Pulmonary Fibrosis (ipf)
Breiburg, A., Lam, K., Dhillon, G., Zone, C., Nicolls, M., & Kuschner, W. (2016). Impact Of Non Invasive Open Ventilation (niov) On Dyspnea And Quality Of Life In Patients With Chronic Obstructive Pulmonary Disease (COPD) And Idiopathic Pulmonary Fibrosis (ipf). AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

A Pro - Con debate: Current Controversies in PAH Pathogenesis at the American Thoracic Society International Meeting in 2017.
Kuebler, W. M., Nicolls, M. R., Olschewski, A., Abe, K., Rabinovitch, M., Stewart, D. J., … Spiekerkoetter, E. (2018). A Pro - Con debate: Current Controversies in PAH Pathogenesis at the American Thoracic Society International Meeting in 2017. American Journal of Physiology. Lung Cellular and Molecular Physiology.

Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis
de Bourcy, C. F. A., Dekker, C. L., Davis, M. M., Nicolls, M. R., & Quake, S. R. (2017). Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis. SCIENCE IMMUNOLOGY, 2(15).

Functional Class Change in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension: Associations with Survival and Exercise Capacity
Chung, L., Parsons, L. S., Hassoun, P. M., McGoon, M. D., Badesch, D. B., Miller, D. P., … Zamanian, R. T. (2011). Functional Class Change in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension: Associations with Survival and Exercise Capacity. ARTHRITIS AND RHEUMATISM, 63(10), S575.

Unique Predictors Of Mortality In Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis In The Reveal Registry (R)
Chung, L., Farber, H. W., Benza, R. L., Miller, D. P., Parsons, L. S., Hassoun, P. M., … Zamanian, R. T. (2013). Unique Predictors Of Mortality In Patients With Pulmonary Arterial Hypertension Associated With Systemic Sclerosis In The Reveal Registry (R). AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.

Refining Definitions Of Time To Clinical Worsening In Connective Tissue Disease Associated Pulmonary Arterial Hypertension
Zamanian, R. T., Chung, L., Parsons, L., Miller, D. P., Safdar, Z., McGoon, M. D., … Frost, A. (2010). Refining Definitions Of Time To Clinical Worsening In Connective Tissue Disease Associated Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181.

Hypoxia Inducible Factor-1 alpha Increases Bone Morphogenetic Protein Receptor 2 Signaling In Pulmonary Artery Endothelial Cells (paecs)
Kuang, J., Tian, X., Prosseda, S. D., Tian, A., Cornfield, D., Nicolls, M. R., & Spiekerkoetter, E. F. (2017). Hypoxia Inducible Factor-1 alpha Increases Bone Morphogenetic Protein Receptor 2 Signaling In Pulmonary Artery Endothelial Cells (paecs). AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195.

Non-Invasive Monitoring of Infection and Rejection After Lung Transplantation
Vlaminck, I. D., Martin, L., Kertesz, M., Patel, K. N., Kowarsky, M., Strehl, C., … Quake, S. R. (2015). Non-Invasive Monitoring of Infection and Rejection After Lung Transplantation. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 34(4), S137.

Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema.
Rockson, S. G., Tian, W., Jiang, X., Kuznetsova, T., Haddad, F., Zampell, J., … Nicolls, M. R. (2018). Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema. JCI Insight, 3(20).

Discovery Of Proteomic Immune Signatures In Pulmonary Arterial Hypertension By Unsupervised Consensus Clustering
Sweatt, A., Hedlin, H., Balasubramanian, V., Hsi, A., Blum, L., Robinson, W., … Zamanian, R. T. (2017). Discovery Of Proteomic Immune Signatures In Pulmonary Arterial Hypertension By Unsupervised Consensus Clustering. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195.

Clinical Heterogeneity Across Proteomic Immunophenotypes In Pulmonary Arterial Hypertension
Sweatt, A., Hedlin, H., Balasubramanian, V., Hsi, A., Blum, L., Robinson, W., … Zamanian, R. T. (2017). Clinical Heterogeneity Across Proteomic Immunophenotypes In Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Delivery Of Il-10 Using A Novel High Molecular Weight Hyaluronan Vehicle Reduces Lung Fibrosis In A Bleomycin Mouse Model Of Lung Injury
Shamskhou, E., Orcholski, M., Kaber, G., Yuan, K., Danielson, B., Chapman, H., … Perez, V. D. J. (2017). Delivery Of Il-10 Using A Novel High Molecular Weight Hyaluronan Vehicle Reduces Lung Fibrosis In A Bleomycin Mouse Model Of Lung Injury. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195.

Leukotriene B4 Potentiates Bmpr2 Deficiency And Causes Paec Endmt In Pah
Tian, A., Jiang, X., Shuffle, E., Tu, A., Jin, Q., Zamanian, R. T., … Nicolls, M. (2017). Leukotriene B4 Potentiates Bmpr2 Deficiency And Causes Paec Endmt In Pah. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195.

Microvascular Integrity Can Be Preserved by Anti-Platelet Therapy and in Combination with mTOR Inhibitor
Heim, C., Khan, M. A., Motsch, B., Gocht, A., Ramsperger-Gleixner, M., Stamminger, T., … Ensminger, S. M. (2017). Microvascular Integrity Can Be Preserved by Anti-Platelet Therapy and in Combination with mTOR Inhibitor. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 36(4), S376.

Donor-Derived Cell-Free DNA Associates with Rejection in Lung Transplantation Using Clinical-Grade Targeted Next-Generation Sequencing
Khush, K. K., Beausang, J. F., Woodward, R. N., Lew, D., Sninsky, J., De Vlaminck, I., … Weill, D. (2017). Donor-Derived Cell-Free DNA Associates with Rejection in Lung Transplantation Using Clinical-Grade Targeted Next-Generation Sequencing. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 36(4), S146.

Lox Inhibitor Synergizes With Cellular Softening By Relaxin To Attenuate Airway Fibrosis In Mouse Orthotopic Tracheal Transplantation Model
Lin, Y., Jiang, X., Khan, M. A., & Nicolls, M. R. (2013). Lox Inhibitor Synergizes With Cellular Softening By Relaxin To Attenuate Airway Fibrosis In Mouse Orthotopic Tracheal Transplantation Model. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.

Limitations Of Pulmonary Vascular Resistance As A Primary Endpoint For Therapeutic Trials Of Systemic Sclerosis Associated Pulmonary Arterial Hypertension
Zamanian, R. T., Rhee, R., Pinckney, A., Goldmuntz, E., Welch, B., D'Aveta, C., … Spychala, M. (2016). Limitations Of Pulmonary Vascular Resistance As A Primary Endpoint For Therapeutic Trials Of Systemic Sclerosis Associated Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Endothelial Hif-2a Deficiency Disrupts Airway Microvascular Structure And Impairs The Repair Of Vessels Of Transplanted Airways
Jiang, X., Tian, W., Tu, A., & Nicolls, M. (2016). Endothelial Hif-2a Deficiency Disrupts Airway Microvascular Structure And Impairs The Repair Of Vessels Of Transplanted Airways. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Acute Microvascular Rejection Increases Graft Iron, Promoting Aspergillus Fumigatus Allograft Invasion
Hsu, J. L., Inayathulla, M., Tu, A. B., Clemons, K. V., Rajadas, J., Stevens, D. A., & Nicolls, M. (2016). Acute Microvascular Rejection Increases Graft Iron, Promoting Aspergillus Fumigatus Allograft Invasion. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Inhibition Of Connective Tissue Growth Factor Promotes Healthy Revascularization And Ameliorates Fibrosis In Orthotopic Tracheal Transplantation
Lin, Y.-C., Jiang, X., & Nicolls, M. (2016). Inhibition Of Connective Tissue Growth Factor Promotes Healthy Revascularization And Ameliorates Fibrosis In Orthotopic Tracheal Transplantation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Bmpr2 Deficiency Potentiates The Ltb4 Mediated Paec Transformation In Pah
Tian, W., Jiang, X., Qian, J., Tu, A., Shuffle, E., Mesange, P., & Nicolls, M. (2016). Bmpr2 Deficiency Potentiates The Ltb4 Mediated Paec Transformation In Pah. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193.

Novel Risk Score Prediction Using Inflammatory Cytokines In Pulmonary Arterial Hypertension
Selej, M., Tian, L., Scalfone, L., Lawrie, A., Nicolls, M. R., Robinson, W., … Zamanian, R. T. (2014). Novel Risk Score Prediction Using Inflammatory Cytokines In Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189.

Hypoxia Inducible Factor-1 alpha Increases Bone Morphogenetic Protein Signaling In Pulmonary Artery Endothelial Cells
Kuang, J., Tian, X., Tian, A., Semenza, G., Nicolls, M. R., & Spiekerkoetter, E. (2015). Hypoxia Inducible Factor-1 alpha Increases Bone Morphogenetic Protein Signaling In Pulmonary Artery Endothelial Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191.

Inhibition Of Nf-kappa b Improves Immune Regulation In The Su5416 And Chronic Hypoxia Model Of Severe Obliterative Pah
Farkas, D., Kraskauskas, D., Kraskauskiene, V., Voelkel, N. F., Fowler, A. A., Natarajan, R., … Farkas, L. (2014). Inhibition Of Nf-kappa b Improves Immune Regulation In The Su5416 And Chronic Hypoxia Model Of Severe Obliterative Pah. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189.

CLOPIDOGREL PRESERVES MICROVASCULAR VASCULAR INTEGRITY IN ORTHOTOPIC TRACHEAL TRANSPLANTS AFFECTED BY OBLITERATIVE BRONCHIOLITIS
Heim, C., Khan, M. A., Motsch, B., Mueller, S., Stamminger, T., Nicolls, M. R., … Ensminger, S. (2014). CLOPIDOGREL PRESERVES MICROVASCULAR VASCULAR INTEGRITY IN ORTHOTOPIC TRACHEAL TRANSPLANTS AFFECTED BY OBLITERATIVE BRONCHIOLITIS. TRANSPLANT INTERNATIONAL, 27, 11.

Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants Affected By Obliterative Bronchiolitis
Heim, C., Khan, M., Motsch, B., Mueller, S., Stamminger, T., Nicolls, M., … Ensminger, S. (2014). Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants Affected By Obliterative Bronchiolitis. AMERICAN JOURNAL OF TRANSPLANTATION, 14, 327.

Relaxin Increases Cellular Softening Which Synergizes With ECM-Softening LOX Inhibitor to Attenuates Airway Fibrosis in Mouse Orthotopic Tracheal Transplantation
Lin, Y., Jiang, X., & Nicolls, M. (2014). Relaxin Increases Cellular Softening Which Synergizes With ECM-Softening LOX Inhibitor to Attenuates Airway Fibrosis in Mouse Orthotopic Tracheal Transplantation. TRANSPLANTATION, 98, 400.

Hypoxia Inducible Factor-1 alpha Limits Aspergillus fumigatus Invasion in the Rejecting Airway Allograft.
Hsu, J., Jiang, X., Clemons, K., Stevens, D., & Nicolls, M. (2014). Hypoxia Inducible Factor-1 alpha Limits Aspergillus fumigatus Invasion in the Rejecting Airway Allograft. TRANSPLANTATION, 98, 270.

Relaxin Increases Cellular Softening Which Synergizes With ECM-Softening LOX Inhibitor to Attenuates Airway Fibrosis in Mouse Orthotopic Tracheal Transplantation
Lin, Y., Jiang, X., & Nicolls, M. (2014). Relaxin Increases Cellular Softening Which Synergizes With ECM-Softening LOX Inhibitor to Attenuates Airway Fibrosis in Mouse Orthotopic Tracheal Transplantation. AMERICAN JOURNAL OF TRANSPLANTATION, 14, 400.

Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants Affected By Obliterative Bronchiolitis.
Heim, C., Khan, M., Motsch, B., Mueller, S., Stamminger, T., Nicolls, M., … Ensminger, S. (2014). Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants Affected By Obliterative Bronchiolitis. TRANSPLANTATION, 98, 327.

Hypoxia Inducible Factor-1 alpha Limits Aspergillus fumigatus Invasion in the Rejecting Airway Allograft.
Hsu, J., Jiang, X., Clemons, K., Stevens, D., & Nicolls, M. (2014). Hypoxia Inducible Factor-1 alpha Limits Aspergillus fumigatus Invasion in the Rejecting Airway Allograft. AMERICAN JOURNAL OF TRANSPLANTATION, 14, 270.

Activation of Classical Complement Pathway is Associated with the Development of Idiopathic Pulmonary Arterial Hypertension (IPAH)
Saito, T., Sharpe, O., Harada, D., Tamosiuniene, R., Li, C. G., Nicolls, M., … Rabinovitch, M. (2012). Activation of Classical Complement Pathway is Associated with the Development of Idiopathic Pulmonary Arterial Hypertension (IPAH). CIRCULATION, 126(21).

Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants affected by Obliterative Bronchiolitis
Heim, C., Khan, M. A., Motsch, B., Mueller, S., Ramsperger-Gleixner, M., Stamminger, T., … Ensminger, S. (2014). Clopidogrel Preserves Microvascular Integrity in Orthotopic Tracheal Transplants affected by Obliterative Bronchiolitis. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 33(4), S255.

Nf-?B Inhibition Prevents Vascular Obliteration and Improves Immune Regulation in Severe Pulmonary Arterial Hypertension
Farkas, D., Alhussaini, A. A., Kraskauskas, D., Kraskauskiene, V., Nicolls, M. R., Voelkel, N. F., … Farkas, L. (2013). Nf-?B Inhibition Prevents Vascular Obliteration and Improves Immune Regulation in Severe Pulmonary Arterial Hypertension. CIRCULATION, 128(22).

The Role Of T Cell Subsets In Tissue Perfusion And Oxygenation In Murine Orthotopic Tracheal Transplant Model Of Airway Allograft Rejection
Khan, M. A., Jiang, X., & Nicolls, M. R. (2010). The Role Of T Cell Subsets In Tissue Perfusion And Oxygenation In Murine Orthotopic Tracheal Transplant Model Of Airway Allograft Rejection. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181.

HIF1 alpha And The Repair Of Injured Airway Microvasculature By Recipient- derived Tie2(+) Cells
Jiang, X., Natarajan, R., Khan, M. A., Krasnow, M., Semenza, G., & Nicolls, M. R. (2010). HIF1 alpha And The Repair Of Injured Airway Microvasculature By Recipient- derived Tie2(+) Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181.

Restoration of Regulatory T Cells (Tregs) Prevents Autoimmune Inflammation (AI) and Pulmonary Hypertension (PH) in Rats
Wang, L., Tamosiuniene, R., Voelkel, N., Gera, L., & Nicolls, M. (2009). Restoration of Regulatory T Cells (Tregs) Prevents Autoimmune Inflammation (AI) and Pulmonary Hypertension (PH) in Rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179.

Murine gamma Herpesvirus-68 Infection Induces Pulmonary Vascular Disease in S100A4 Overexpressing Mice Associated with Susceptibility of Elastic Fibers to Degradation and Altered microRNA Expression.
Kim, Y.-M., Alvira, C., Wang, L., & Rabinovitch, M. (2009). Murine gamma Herpesvirus-68 Infection Induces Pulmonary Vascular Disease in S100A4 Overexpressing Mice Associated with Susceptibility of Elastic Fibers to Degradation and Altered microRNA Expression. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179.

The Role of Complement Activation on Tissue Perfusion and Oxygenation in Airway Allograft Rejection
Khan, M. A., Tomlinson, S., Xinguo, J., & Nicolls, M. R. (2010). The Role of Complement Activation on Tissue Perfusion and Oxygenation in Airway Allograft Rejection. AMERICAN JOURNAL OF TRANSPLANTATION, 10, 4.

Glycan expression profile in freshly isolated pancreatic islets
Fontaine, M. J., Kvezereli, M., Nicolls, M. R., & Wang, D. (2010). Glycan expression profile in freshly isolated pancreatic islets. ANNALS OF CLINICAL AND LABORATORY SCIENCE, 40(2), 188.

The Role of Hypoxia Inducible Factors in Maintenance of Airway Epithelial Health
Pasupneti, S., Tian, A., Jiang, X., & Nicolls, M. R. (2018). The Role of Hypoxia Inducible Factors in Maintenance of Airway Epithelial Health. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197.

Endothelial HIF-2 alpha Maintains Airway Microvasculature Through Angiopoietin-1/TIE2 Signaling
Tu, A., Jiang, X., Tian, W., & Nicolls, M. R. (2018). Endothelial HIF-2 alpha Maintains Airway Microvasculature Through Angiopoietin-1/TIE2 Signaling. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197.

Increased Lymphangiogenesis in Animal Models of Pulmonary Arterial Hypertension
Zhang, P., Tian, A. W., Tu, A. B., Jiang, X., & Nicolls, M. R. (2018). Increased Lymphangiogenesis in Animal Models of Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197.

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.
Humbert, M., Guignabert, C., Bonnet, S., Dorfmüller, P., Klinger, J. R., Nicolls, M. R., … Rabinovitch, M. (2018). Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. The European Respiratory Journal.

Loss of Endothelial Derived WNT5A is Associated with Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension.
Yuan, K., Shamskhou, E. A., Orcholski, M. E., Nathan, A., Reddy, S., Honda, H., … de Jesus Perez, V. A. (2018). Loss of Endothelial Derived WNT5A is Associated with Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension. Circulation.

Endothelial HIF-2alpha is Required for the Maintenance of Airway Microvasculature.
Jiang, X., Tian, W., Tu, A. B., Pasupneti, S., Shuffle, E., Dahms, P., … Nicolls, M. R. (2018). Endothelial HIF-2alpha is Required for the Maintenance of Airway Microvasculature. Circulation.

Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension.
Sweatt, A. J., Hedlin, H. K., Balasubramanian, V., Hsi, A., Blum, L. K., Robinson, W. H., … Zamanian, R. T. (2019). Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension. Circulation Research.

Preservation of microvascular integrity in murine orthotopic tracheal allografts by clopidogrel.
Heim, C., Khan, M. A., Silva-Tarouca, B. von, Kuckhahn, A., Stamminger, T., Ramsperger-Gleixner, M., … Ensminger, S. M. (2019). Preservation of microvascular integrity in murine orthotopic tracheal allografts by clopidogrel. Transplantation.

Change in diffusing capacity for carbon monoxide as a predictor of outcomes in connective tissue disease-associated pulmonary arterial hypertension: Analysis from the REVEAL registry
Zamanian, R., Kudelko, K., Miller, D., McGoon, M., Benza, R., Hassoun, P., … Chung, L. (2012). Change in diffusing capacity for carbon monoxide as a predictor of outcomes in connective tissue disease-associated pulmonary arterial hypertension: Analysis from the REVEAL registry. EUROPEAN RESPIRATORY JOURNAL. EUROPEAN RESPIRATORY SOC JOURNALS LTD.

Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States.
Mooney, J. J., Hedlin, H., Mohabir, P. K., Vazquez, R., Nguyen, J., Ha, R., … Dhillon, G. S. (2016). Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3.
Wu, T.-H. H., Shi, L., Lowe, A. W., Nicolls, M. R., & Kao, P. N. (2019). Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3. PloS One, 14(4), e0216042.

Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema
Rockson, S. G., Tian, W., Jiang, X., Kuznetsova, T., Haddad, F., Zampell, J., … Nicolls, M. R. (2018). Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema. JCI INSIGHT, 3(20).

Anti-hyperlipidaemic effects of synthetic analogues of nordihydroguaiaretic acid in dyslipidaemic rats
Singh, M., Bittner, S., Li, Y., Bittner, A., Han, L., Cortez, Y., … Azhar, S. (2019). Anti-hyperlipidaemic effects of synthetic analogues of nordihydroguaiaretic acid in dyslipidaemic rats. BRITISH JOURNAL OF PHARMACOLOGY, 176(3), 369–85.

Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension
Blum, L. K., Cao, R. R. L., Sweatt, A. J., Bill, M., Lahey, L. J., Hsi, A. C., … Robinson, W. H. (2018). Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. EUROPEAN JOURNAL OF IMMUNOLOGY, 48(5), 874–84.

HIF1 alpha-Mediated Lymphangiogenesis Influences Airway Transplant Rejection
Tu, A. B., Jiang, X., Tian, A., Dahms, P., Zhang, P., Pasupneti, S., & Nicolls, M. R. (2019). HIF1 alpha-Mediated Lymphangiogenesis Influences Airway Transplant Rejection. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199.

The Role of Iron-Induced Macrophage Dysregulation in Aspergillus Fumigatus Invasion in Airway Transplantation
Matthaiou, E., Manouvakhova, O. M., Sinha, M., Tu, A. B., Clemons, K. V., Stevens, D. A., … Hsu, J. L. (2019). The Role of Iron-Induced Macrophage Dysregulation in Aspergillus Fumigatus Invasion in Airway Transplantation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199.

High Dose Ubenimex Interferes with the Efficacy of Sildenafil in Experimental Pulmonary Hypertension
Dahms, P., Tian, A., Zhang, P., Tu, A. B., Jiang, X., Pasupneti, S., … Nicolls, M. R. (2019). High Dose Ubenimex Interferes with the Efficacy of Sildenafil in Experimental Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199.

Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3
Wu, T.-H., Shi, L., Lowe, A. W., Nicolls, M. R., & Kao, P. N. (2019). Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3. PLOS ONE, 14(4).

Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension
Sweatt, A. J., Hedlin, H. K., Balasubramanian, V., Hsi, A., Blum, L. K., Robinson, W. H., … Zamanian, R. T. (2019). Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension. CIRCULATION RESEARCH, 124(6), 904–19.

Loss of Endothelium-Derived Wnt5a Is Associated With Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension
Yuan, K., Shamskhou, E. A., Orcholski, M. E., Nathan, A., Reddy, S., Honda, H., … Perez, V. A. de J. (2019). Loss of Endothelium-Derived Wnt5a Is Associated With Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension. CIRCULATION, 139(14), 1710–24.

Airway hypoxia in lung transplantation
Pasupneti, S., & Nicolls, M. R. (2019). Airway hypoxia in lung transplantation. CURRENT OPINION IN PHYSIOLOGY, 7, 21–26.

Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation.
Tian, W., Jiang, X., Sung, Y. K., Shuffle, E., Wu, T.-H. H., Kao, P. N., … Nicolls, M. R. (2019). Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation. Circulation.

Preservation of Microvascular Integrity in Murine Orthotopic Tracheal Allografts by Clopidogrel
Heim, C., Khan, M. A., von Silva-Tarouca, B., Kuckhahn, A., Stamminger, T., Ramsperger-Gleixner, M., … Ensminger, S. M. (2019). Preservation of Microvascular Integrity in Murine Orthotopic Tracheal Allografts by Clopidogrel. TRANSPLANTATION, 103(5), 899–908.

The Lymphatic System in Obesity, Insulin Resistance, and Cardiovascular Diseases.
Jiang, X., Tian, W., Nicolls, M. R., & Rockson, S. G. (2019). The Lymphatic System in Obesity, Insulin Resistance, and Cardiovascular Diseases. Frontiers in Physiology, 10, 1402.

Late Breaking Abstract - Safety and efficacy of B-cell depletion with rituximab for the treatment of systemic sclerosis-associated pulmonary arterial hypertension
Zamanian, R., Badesch, D., Chung, L., Domsic, R., Medsger, T., Pinckney, A., … Nicolls, M. (2019). Late Breaking Abstract - Safety and efficacy of B-cell depletion with rituximab for the treatment of systemic sclerosis-associated pulmonary arterial hypertension. EUROPEAN RESPIRATORY JOURNAL. EUROPEAN RESPIRATORY SOC JOURNALS LTD.

Safety and Efficacy of B-cell Depletion with Rituximab for the Treatment of Systemic Sclerosis-associated Pulmonary Arterial Hypertension in a Multi-center NIH Clinical Trial
Nicolls, M., Badesch, D., Chung, L., Domsic, R., Medsger, T., Pinckney, A., … Zamanian, R. (2019). Safety and Efficacy of B-cell Depletion with Rituximab for the Treatment of Systemic Sclerosis-associated Pulmonary Arterial Hypertension in a Multi-center NIH Clinical Trial. ARTHRITIS & RHEUMATOLOGY. WILEY.

The Hallmarks of Severe Pulmonary Arterial Hypertension: The Cancer Hypothesis - Ten years later.
Cool, C. D., Kuebler, W. M., Bogaard, H. J., Spiekerkoetter, E., Nicolls, M. R., & Voelkel, N. F. (2020). The Hallmarks of Severe Pulmonary Arterial Hypertension: The Cancer Hypothesis - Ten years later. American Journal of Physiology. Lung Cellular and Molecular Physiology.

Mural Cell SDF1 Signaling is Associated with the Pathogenesis of Pulmonary Arterial Hypertension.
Yuan, K., Liu, Y., Zhang, Y., Nathan, A., Tian, W., Yu, J., … de Jesus Perez, V. A. (2020). Mural Cell SDF1 Signaling is Associated with the Pathogenesis of Pulmonary Arterial Hypertension. American Journal of Respiratory Cell and Molecular Biology.

Machine learning algorithms to differentiate among pulmonary complications after hematopoietic cell transplant.
Sharifi, H., Lai, Y. K., Guo, H., Hoppenfeld, M., Guenther, Z. D., Johnston, L., … Hsu, J. L. (2020). Machine learning algorithms to differentiate among pulmonary complications after hematopoietic cell transplant. Chest.

Endothelial HIF-2alpha as a Key Endogenous Mediator Preventing Emphysema.
Pasupneti, S., Tian, W., Tu, A. B., Dahms, P., Granucci, E., Gandjeva, A., … Nicolls, M. R. (2020). Endothelial HIF-2alpha as a Key Endogenous Mediator Preventing Emphysema. American Journal of Respiratory and Critical Care Medicine.

Decreased lymphatic HIF-2a accentuates lymphatic remodeling in lymphedema.
Jiang, X., Tian, W., Granucci, E. J., Tu, A. B., Kim, D., Dahms, P., … Nicolls, M. R. (2020). Decreased lymphatic HIF-2a accentuates lymphatic remodeling in lymphedema. The Journal of Clinical Investigation.

From 2D to 3D: Promising Advances in Imaging Lung Structure.
Klouda, T., Condon, D., Hao, Y., Tian, W., Lvova, M., Chakraborty, A., … Yuan, K. (2020). From 2D to 3D: Promising Advances in Imaging Lung Structure. Frontiers in Medicine, 7, 343.

Single-Cell RNA-seq Analysis Reveals Endothelial Heterogeneity of Inflammation-Induced Pulmonary Arterial Hypertension Under Bmpr2 Dysfunction
Wu, T., Peng, G., Tian, A., Guan, T., & Nicolls, M. R. (2020). Single-Cell RNA-seq Analysis Reveals Endothelial Heterogeneity of Inflammation-Induced Pulmonary Arterial Hypertension Under Bmpr2 Dysfunction. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201.

Bone Morphogenetic Protein Receptor 2 Mutations Impair T Regulatory Cell Function and Promote Inflammation in Pulmonary Arterial Hypertension
Peng, G., Tian, A., Guan, T., Wu, T., & Nicolls, M. R. (2020). Bone Morphogenetic Protein Receptor 2 Mutations Impair T Regulatory Cell Function and Promote Inflammation in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201.

Leukotrienes in Tumor-Associated Inflammation
Tian, W., Jiang, X., Kim, D., Guan, T., Nicolls, M. R., & Rockson, S. G. (2020). Leukotrienes in Tumor-Associated Inflammation. FRONTIERS IN PHARMACOLOGY, 11.

Leukotrienes in Tumor-Associated Inflammation.
Tian, W., Jiang, X., Kim, D., Guan, T., Nicolls, M. R., & Rockson, S. G. (2020). Leukotrienes in Tumor-Associated Inflammation. Frontiers in Pharmacology, 11, 1289.

IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis.
Mbanefo, E. C., Agbo, C. T., Zhao, Y., Lamanna, O. K., Thai, K. H., Karinshak, S. E., … Hsieh, M. H. (2020). IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis. Infectious Agents and Cancer, 15, 63.

Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation.
Khush, K. K., De Vlaminck, I., Luikart, H., Ross, D. J., & Nicolls, M. R. (2021). Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation. ERJ Open Research, 7(1).

Microvasculature in murine tracheal allografts after combined therapy with clopidogrel and everolimus.
Heim, C., Kuckhahn, A., Ramsperger-Gleixner, M., Nicolls, M. R., Weyand, M., & Ensminger, S. M. (2021). Microvasculature in murine tracheal allografts after combined therapy with clopidogrel and everolimus. Interactive Cardiovascular and Thoracic Surgery.

Safety and Efficacy of B-Cell Depletion with Rituximab for the Treatment of Systemic Sclerosis Associated Pulmonary Arterial Hypertension: A Multi-center, Double-blind, Randomized, Placebo-controlled Trial.
Zamanian, R. T., Badesch, D., Chung, L., Domsic, R. T., Medsger, T., Pinckney, A., … Nicolls, M. R. (2021). Safety and Efficacy of B-Cell Depletion with Rituximab for the Treatment of Systemic Sclerosis Associated Pulmonary Arterial Hypertension: A Multi-center, Double-blind, Randomized, Placebo-controlled Trial. American Journal of Respiratory and Critical Care Medicine.

Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances.
Maron, B. A., Abman, S. H., Elliott, C. G., Frantz, R. P., Hopper, R. K., Horn, E. M., … Rosenzweig, E. B. (2021). Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances. American Journal of Respiratory and Critical Care Medicine.

The Kinetics of Lymphatic Dysfunction and Leukocyte Expansion in the Draining Lymph Node during LTB4 Antagonism in a Mouse Model of Lymphedema.
Cribb, M. T., Sestito, L. F., Rockson, S. G., Nicolls, M. R., Thomas, S. N., & Dixon, J. B. (2021). The Kinetics of Lymphatic Dysfunction and Leukocyte Expansion in the Draining Lymph Node during LTB4 Antagonism in a Mouse Model of Lymphedema. International Journal of Molecular Sciences, 22(9).

Reply to: Multiple Manifestations of Systemic Sclerosis Affect Walk Distance.
Zamanian, R. T., Pinckney, A., Domsic, R. T., Medsger, T., Keyes-Elstein, L., Sweatt, A. J., … Chung, L. (2021). Reply to: Multiple Manifestations of Systemic Sclerosis Affect Walk Distance. American Journal of Respiratory and Critical Care Medicine.

Severe Pulmonary Arterial Hypertension is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.
Sweatt, A. J., Miyagawa, K., Rhodes, C. J., Taylor, S., Del Rosario, P. A., Hsi, A., … Zamanian, R. T. (2021). Severe Pulmonary Arterial Hypertension is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency. Chest.

The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions.
Nakahara, M., Ito, H., Skinner, J. T., Lin, Q., Tamosiuniene, R., Nicolls, M. R., … Yamaji-Kegan, K. (2021). The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions. American Journal of Physiology. Lung Cellular and Molecular Physiology.

The COVID-19 Outpatient Pragmatic Platform Study (COPPS): Study design of a multi-center pragmatic platform trial.
Bunning, B., Hedlin, H., Purington, N., Sundaram, V., Kapphahn, K., Weng, Y., … Desai, M. (2021). The COVID-19 Outpatient Pragmatic Platform Study (COPPS): Study design of a multi-center pragmatic platform trial. Contemporary Clinical Trials, 106509.

The Role of Regulatory T Cells in Pulmonary Arterial Hypertension.
Tian, W., Jiang, S. Y., Jiang, X., Tamosiuniene, R., Kim, D., Guan, T., … Nicolls, M. R. (2021). The Role of Regulatory T Cells in Pulmonary Arterial Hypertension. Frontiers in Immunology, 12, 684657.

Colorectal Cancer-Associated Microbiome Patterns and Signatures.
Zhao, L., Cho, W. C., & Nicolls, M. R. (1800). Colorectal Cancer-Associated Microbiome Patterns and Signatures. Frontiers in Genetics, 12, 787176.

Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension
Tamosiuniene, R., Manouvakhova, O., Mesange, P., Saito, T., Qian, J., Sanyal, M., … Nicolls, M. R. (2018). Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension. CIRCULATION RESEARCH, 122(12), 1689–1702.

Exploring disease interrelationships in patients with lymphatic disorders: A single center retrospective experience.
Rockson, S. G., Zhou, X., Zhao, L., Hosseini, D. K., Jiang, X., Sweatt, A. J., … Nicolls, M. R. (2022). Exploring disease interrelationships in patients with lymphatic disorders: A single center retrospective experience. Clinical and Translational Medicine, 12(4), e760.

Hypoxia and Hypoxia-Inducible Factors in Lymphedema.
Jiang, X., Tian, W., Kim, D., McQuiston, A. S., Vinh, R., Rockson, S. G., … Nicolls, M. R. (2022). Hypoxia and Hypoxia-Inducible Factors in Lymphedema. Frontiers in Pharmacology, 13, 851057.

CES1 Deficiency Is Associated with Oxidative Stress Mediated Endoplasmic Reticulum/Mitochondrial Dysfunction in Pulmonary Endothelial Cells
Agarwal, S. S., Chakraborty, A., Shamskhou, E., Condon, D. F., Suresh, K., Rabinovitch, M., … Perez, V. D. J. (2022). CES1 Deficiency Is Associated with Oxidative Stress Mediated Endoplasmic Reticulum/Mitochondrial Dysfunction in Pulmonary Endothelial Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction
Kim, D., Zhao, L., Wu, T., Vihn, R., Schneider, E., Cunningham, C. M., … Nicolls, M. R. (2022). Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Divergent Roles of Lymphatic Endothelial Cell-Expressed Hypoxia-Inducible Factors in Airway Transplant Rejection
Mcquiston, A. S., Kim, D., Vihn, R., Schneider, E. C., Tian, W., Jiang, X., & Nicolls, M. R. (2022). Divergent Roles of Lymphatic Endothelial Cell-Expressed Hypoxia-Inducible Factors in Airway Transplant Rejection. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Overexpression of Pericyte HIF2 alpha Exacerbates Hypoxia Induced Pulmonary Hypertension and Right Ventricular Hypertrophy
Kim, H., Liu, Y., Kim, J., Klouda, T., Hu, C., Tian, W., … Yuan, K. (2022). Overexpression of Pericyte HIF2 alpha Exacerbates Hypoxia Induced Pulmonary Hypertension and Right Ventricular Hypertrophy. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

The role of circular RNAs in pulmonary hypertension.
Ali, M. K., Schimmel, K., Zhao, L., Chen, C.-K. K., Dua, K., Nicolls, M. R., & Spiekerkoetter, E. (2022). The role of circular RNAs in pulmonary hypertension. The European Respiratory Journal.

Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension.
Taylor, S., Isobe, S., Cao, A., Contrepois, K., Benayoun, B. A., Jiang, L., … Rabinovitch, M. (2022). Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine.

Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections.
Kratochvil, M. J., Kaber, G., Demirdjian, S., Cai, P. C., Burgener, E. B., Nagy, N., … Bollyky, P. L. (2022). Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections. JCI Insight, 7(12).

Biochemical, Biophysical, and Immunological Characterization of Respiratory Secretions in Severe SARS-CoV-2 (COVID-19) Infections.
Kratochvil, M. J., Kaber, G., Demirdjian, S., Cai, P. C., Burgener, E. B., Nagy, N., … Bollyky, P. L. (2022). Biochemical, Biophysical, and Immunological Characterization of Respiratory Secretions in Severe SARS-CoV-2 (COVID-19) Infections. MedRxiv : the Preprint Server for Health Sciences.

Endothelial Hypoxia-Inducible Factor-2 Is Required for the Maintenance of Airway Microvasculature
Jiang, X., Tian, W., Tu, A. B., Pasupneti, S., Shuffle, E., Dahms, P., … Nicolls, M. R. (2019). Endothelial Hypoxia-Inducible Factor-2 Is Required for the Maintenance of Airway Microvasculature. CIRCULATION, 139(4), 502–517.

The Human Respiratory Microbiome: Current Understandings and Future Directions.
Zhao, L., Luo, J.-L. L., Ali, M. K., Spiekerkoetter, E., & Nicolls, M. R. (2022). The Human Respiratory Microbiome: Current Understandings and Future Directions. American Journal of Respiratory Cell and Molecular Biology.

Endotyping COPD: hypoxia-inducible factor-2 as a molecular "switch" between the vascular and airway phenotypes?
Myronenko, O., Foris, V., Crnkovic, S., Olschewski, A., Rocha, S., Nicolls, M. R., & Olschewski, H. (2023). Endotyping COPD: hypoxia-inducible factor-2 as a molecular "switch" between the vascular and airway phenotypes? European Respiratory Review : an Official Journal of the European Respiratory Society, 32(167).

PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Ali, M. K., Tian, X., Zhao, L., Schimmel, K., Rhodes, C. J., Wilkins, M. R., … Spiekerkoetter, E. F. (2023). PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. Cells, 12(2).

A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3.
Bhagwani, A. R., Ali, M., Piper, B., Liu, M., Hudson, J., Kelly, N., … Farkas, L. (2023). A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3. IScience, 26(2), 105935.

Evaluation of acebilustat, a selective inhibitor of leukotriene B4 biosynthesis, for treatment of outpatients with mild-moderate COVID-19 disease: A randomized, double-blind, placebo- controlled Phase 2 trial.
Levitt, J. E., Hedlin, H., Duong, S., Lu, D., Lee, J., Bunning, B., … Rogers, A. J. (2023). Evaluation of acebilustat, a selective inhibitor of leukotriene B4 biosynthesis, for treatment of outpatients with mild-moderate COVID-19 disease: A randomized, double-blind, placebo- controlled Phase 2 trial. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America.

Decreasing ELK3 expression improves Bone Morphogenetic Protein Receptor 2 signaling and pulmonary vascular cell function in PAH.
Ali, M. K., Zhao, L., Perez, V. de J., Nicolls, M. R., & Spiekerkoetter, E. F. (2023). Decreasing ELK3 expression improves Bone Morphogenetic Protein Receptor 2 signaling and pulmonary vascular cell function in PAH. BioRxiv : the Preprint Server for Biology.

PANEL OF MONOCLONAL-ANTIBODIES DIRECTED AGAINST RAT T-LYMPHOCYTES
NICOLLS, M. R., AVERSA, G. A., & HALL, B. M. (1990). PANEL OF MONOCLONAL-ANTIBODIES DIRECTED AGAINST RAT T-LYMPHOCYTES. CLINICAL RESEARCH. SLACK INC.

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
Humbert, M., Guignabert, C., Bonnet, S., Dorfmuller, P., Klinger, J. R., Nicolls, M. R., … Rabinovitch, M. (2019). Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. EUROPEAN RESPIRATORY JOURNAL. EUROPEAN RESPIRATORY SOC JOURNALS LTD.

ANTI-CD3 MONOCLONAL-ANTIBODY INDUCES TOLERANCE TO ALLOANTIGENS IN RATS
NICOLLS, M. R., AVERSA, G. G., PEARCE, N. W., SPINELLI, A., BERGER, M. F., GURLEY, K. E., & HALL, B. M. (1991). ANTI-CD3 MONOCLONAL-ANTIBODY INDUCES TOLERANCE TO ALLOANTIGENS IN RATS. CLINICAL RESEARCH. SLACK INC.

ROLE OF T-CELLS IN HEYMANN NEPHRITIS
QUIZA, C., GURLEY, K. E., SPINELLI, A., LEENAERTS, P., NICOLLS, M., & HALL, B. M. (1991). ROLE OF T-CELLS IN HEYMANN NEPHRITIS. CLINICAL RESEARCH. SLACK INC.

Abnormal lymphatic S1P signaling aggravates lymphatic dysfunction and tissue inflammation.
Kim, D., Tian, W., Wu, T. T.-H., Xiang, M., Vinh, R., Chang, J., … Nicolls, M. R. (2023). Abnormal lymphatic S1P signaling aggravates lymphatic dysfunction and tissue inflammation. MedRxiv : the Preprint Server for Health Sciences.

Abnormal Lymphatic Sphingosine-1-Phosphate Signaling Aggravates Lymphatic Dysfunction and Tissue Inflammation.
Kim, D., Tian, W., Wu, T. T.-H., Xiang, M., Vinh, R., Chang, J. L., … Nicolls, M. R. (2023). Abnormal Lymphatic Sphingosine-1-Phosphate Signaling Aggravates Lymphatic Dysfunction and Tissue Inflammation. Circulation.

A Selective Leukotriene B4 Antagonist, Acebilustat, for Treatment of Outpatients With COVID-19 Disease: A Randomized, Double-blind, Placebo-controlled Phase 2 Trial
Levitt, J. E., Hedlin, H., Duong, S., Lu, D., Lee, J., Elkarra, N., … Rogers, A. (2023). A Selective Leukotriene B4 Antagonist, Acebilustat, for Treatment of Outpatients With COVID-19 Disease: A Randomized, Double-blind, Placebo-controlled Phase 2 Trial. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Using an Unsupervised Learning Ensemble to Identify and Evaluate PAH Immune Phenotypes Longitudinally During Disease Progression
Sweatt, A., Hedlin, H. K., Haddad, F., Lawrie, A., Desai, M., Khatri, P., … Zamanian, R. T. (2023). Using an Unsupervised Learning Ensemble to Identify and Evaluate PAH Immune Phenotypes Longitudinally During Disease Progression. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy.
Ferrian, S., Cao, A., McCaffrey, E. F., Saito, T., Greenwald, N. F., Nicolls, M. R., … Angelo, M. (2023). Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy. American Journal of Respiratory and Critical Care Medicine.

Pericytes contribute to pulmonary vascular remodeling via HIF2a signaling.
Kim, H., Liu, Y., Kim, J., Kim, Y., Klouda, T., Fisch, S., … Yuan, K. (2024). Pericytes contribute to pulmonary vascular remodeling via HIF2a signaling. EMBO Reports.

Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs.
Zhao, L., Cunningham, C. M., Andruska, A. M., Schimmel, K., Ali, M. K., Kim, D., … Nicolls, M. R. (2024). Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs. Lab Animal, 53(2), 43–55.

B cells in pulmonary arterial hypertension: friend, foe or bystander?
Sanges, S., Tian, W., Dubucquoi, S., Chang, J. L., Collet, A., Launay, D., & Nicolls, M. R. (2024). B cells in pulmonary arterial hypertension: friend, foe or bystander? The European Respiratory Journal.

VIEWING PULMONARY HYPERTENSION THROUGH A PEDIATRIC LENS.
Agarwal, S., Fineman, J., Cornfield, D. N., Alvira, C. M., Zamanian, R. T., Goss, K., … de Jesús Pérez, V. (2024). VIEWING PULMONARY HYPERTENSION THROUGH A PEDIATRIC LENS. The European Respiratory Journal.